An Australian stem cell and regenerative medicine company
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Science Publications
Chakraborty et al. Induced pluripotent stem cell-derived mesenchymal stem cells reverse bleomycin-induced pulmonary fibrosis and related lung stiffness. Biomedicine & Pharmacotherapy, 2024
Kelly K et al. Two-year safety outcomes of iPS cell-derived mesenchymal stromal cells in acute steroid-resistant graft-versus-host disease. Nat Med. 2024
Hodgson-Garms M et al. A comparative analysis of the MSC transcriptome: Human iPSC-derived MSCs and their tissue-derived counterparts. ASSCR 2022 Poster.
Romanazzo S et al. Biomaterials directed activation of a cryostable therapeutic secretome in iPSC derived MSCs. Tissue Eng Regen Med. 2022;16(11):1008-1018.
Liu X et al. Efficacy and cost-effectiveness of stem cell injections for symptomatic relief and structural improvement in people with tibiofemoral knee osteoarthritis. BMJ Open. 2021;11(11):e056382
Kelly K, Rasko JEJ. Mesenchymal Stromal Cells for the Treatment of Graft Versus Host Disease. Front Immunol. 2021;12:761616.
Thavapalachandran S et al. Pluripotent stem cell-derived mesenchymal stromal cells improve cardiac function and vascularity after myocardial infarction. Cytotherapy. 2021;23(12):1074-1084.
Bloor AJC et al. Production, safety and efficacy of iPSC-derived MSCs in acute steroid-resistant graft versus host disease: a phase I study. Nat Med. 2020;26(11):1720-1725.
Millar JE et al. Combined MSC and Therapy and ECMO in Acute Respiratory Distress Syndrome. A Randomized Controlled Trial in Sheep. Am J Respir Crit Care Med. 2020;202(3):383-392.
Rasko JEJ et al. Results of the First Completed Clinical Trial of an iPSC-Derived Product: CYP-001 in Steroid-Resistant Acute GvHD. TCT 2019 Poster.
Khan MA et al. iPSC-derived MSC therapy induces immune tolerance and supports long-term graft survival in mouse orthotopic tracheal transplants. Stem Cell Res Ther. 2019;23;10(1):290.
Royce SG et al. iPSC- and MCA-derived MSCs provide greater protection against experimental chronic allergic airways disease compared with a clinically used corticosteroid. FASEB J. 2019;33:6402-11.
Kelly K. Can iPSCs Address the Challenge of Maintaining Consistent Quality in Starting Materials Used in the Manufacture of Cell-Based Therapies? Cell & Gene Therapy Insights. 2019; 5(2), 227-232.
Ozay EI et al. Cymerus™ iPSC-MSCs significantly prolong survival in a pre-clinical, humanized mouse model of Graft-vs-host disease. Stem Cell Res. 2019;35:101401.
Kelly K. Next-generation cell-based therapies: the potential of IPSCs. Australasian Biotechnology. 2017;27(3):14-16.
Royce SG et al. Intranasal administration of MCA-derived MSCs abrogates airway fibrosis and airway hyperresponsiveness associated with chronic allergic airways disease. FASEB J. 2017;31(9):4168-4178.
Koch JM et al. MCA-derived MSCs inhibit cell damage, tissue damage and improve peripheral blood flow following hindlimb ischemic injury in mice. Cytotherapy 2016;18:219–228.
Kelly K. Limitless starting materials for large-scale manufacture of MSCs – what does the future hold? Pharm Bioprocess. 2015;3:281-283.
Vodyanik MA et al. A Mesoderm-Derived Precursor for Mesenchymal Stem and Endothelial Cells. Cell Stem Cell 2010;7(6):718-29.