Announcement PDF Form 604 Corporations Act 2001 Section 671B Notice of Change of Interests of Substantial Holder To: CYNATA THERAPEUTICS LIMITED ACN/ARSN: 1. Details of substantial holder (1) Name: FIL Limited and its entities listed in Annexure A ("FIL") ACN/ARSN (if applicable) There was a change in the interests of the substantial holder on 29 June 2026 The previous notice was given to the company on 26 August 2025 The previous notice was dated 26 August 2025 2. Previous and present voting power The total number of votes attached to all the voting shares in the company or voting interests in the scheme that the substantial holder or an associate (2) had a relevant interest (3) in when last required, and when now required, to give a substantial holding notice to the company or scheme, are as follows: Class of Securities (4) Previous Notice Person’s votes Previous Notice Voting Power (5) Present Notice Person’s votes Present Notice Voting Power (5) COMMON STOCK 20,967,806 8.83% 15,526,501 6.38% 3. Changes in relevant interests Particulars of each change in, or change in the nature of, a relevant interest of the substantial holder or an associate in voting securities of the company or scheme, since the substantial holder was last required to give a substantial holding notice to the company or scheme are as follows: Date of Change Person whose relevant interest changed Nature of change (6) Consideration given in relation to change (7) Class and number of securities affected Person’s votes affected AUD$ Common Stock Common Stock 05/05/2026 FIL BUY 0.2500 335,921 335,921 05/05/2026 FIL BUY 0.2500 36,631 36,631 05/05/2026 FIL BUY 0.2500 56,114 56,114 05/05/2026 FIL BUY 0.2500 101,151 101,151 26/06/2026 FIL SELL 0.0140 286,844 286,844 29/06/2026 FIL SELL 0.0128 3,497,872 3,497,872 29/06/2026 FIL SELL 0.0128 566,575 566,575 29/06/2026 FIL SELL 0.0128 566,575 566,575 29/06/2026 FIL SELL 0.0128 1,053,256 1,053,256 4. Present Relevant Interest Particulars of each relevant interest of the substantial holder in voting securities after the change are as follows: Refer to Annexure A 5. Changes in Association The persons who have become associates (2) of, ceased to be associates of, or have changed the nature of their association (9) with, the substantial holder in relation to voting interests in the company or scheme are as follows: Name and ACN/ARSN (if applicable) Nature of association N/A 6. Addresses The addresses of persons named in this form are as follows: The address of FIL Limited is Pembroke Hall, 42 Crow Lane, Pembroke, HM 19, Bermuda and please refer to Annexure A for its entity with relevant interest Sign Here _____________________________ Dated: 01 July 2026 Alina Yu Regulatory Reporting Manager Duly authorized under Powers of Attorney by and on behalf of FIL Limited Annexure A Investment Manager Address Custodian Nature of Relevant Interest Sum of Numerator Shares FIL Investment Management (Hong Kong) Limited Level 21, Two Pacific Place, 88 Queensway, Admiralty, Hong Kong BROWN BROS HARRIMN LTD LUX (C) Investment Discretion / Voting Power 10,132,366 CLEARSTREAM BANKING SA LUX (C) 3,050,992 LANDESBANK BADEN-WUERTTEMBERG 2,343,143 Grand Total 15,526,501